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一、名词解释(应该是5个,但是记不清是哪5个了) f CU]
1.chaperon 2.motif 3.allosteric enzyme 4.ribozyme 5.gluconeogenesis 6.sernicon servativereplication @Z~YFnEJi
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二、选择题(很多题记不太清楚了,细节问题请包容) DhyR
1.Which of the followingstatements concerning protein domains is true? SOOVUMj
A.they are examples ofstructural motifs |4df)
B.large polypeptide may beorganized into struoturally close but functionally independent units
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C.the consist of separatepoly peptide chains(subunits) JsJP%'^/R
D.they have been found onlyin prokaryotic proteins Dkz/hg:q
2.Prion disease aregenerally believed to a associated with cRT'?w`}
A.infection by a RNA vins B.infection by DNA C.infection by protein D.infection by mRNA f{P1.?a
3.The secondary structureof transfer RNA is Ehx9-*]
A.described as double helix B.described as reversed “L” C.described as cloverleaf D.present only ineukaryotic cells i0=U6S:#
4.In competitive inhibiyion ,s[%,ep`
A.Km not change,Vmax not change B.Km rise, Vmaxnot change C.Km not change,Vmax rise D.Km rise, Vmaxrise aK_5@8+ZD
5.The part og the RNApolymerase noloenzyme that initiates binding to DNA is called the lz,M$HG<[
A.sigma factor B.intron C.ribosomal RNA D.core enzyme ;st0Ekni)
6.Sunlight can damage DNAby 53i]Q;k [
A.making apyrimidinic sites B.causing spontaneousdeamination of bases t(z]4y
C.forming pyrimidinedimmers D.alkylating DNA 2aYBcPFQh#
7.Which is therate-limiting enzyme, inregulation of the pentose phosphate pathway? %(YQ)=w
A.hexokinase B.6-phosphofructokinace-1 C.Clucose-6-phosphatedehydrogenase D.pyrurate dehydrogenase 6
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8.Transcription is theprocess in which p!UR;xH
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A.protein is synthesized from DNA B.DNA is replicated o2!738
C.RNA is synthesized from protein D.ENA is synthesized fromDNA 5XK
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9.Which of the following isa sis-acting element? ( /]'e}
A.RNA polymerase B.Enhancer C.transcriptionfactor I D.structural gene d[a(uWEl
10.The protein that canbind to RNA and prevent the trascription is called J2z/XHS
A.inducer B.repressor protein C.cis-acting element D.positive regulatoryproteins 2R/|/>T v
11.蛋白质吸收紫外光的大小取决于 MmT/J1zM
A.脂肪族氨基酸含量 B.酸性氨基酸含量 C.芳香族氨基酸含量 D. 蛋氨酸含量 FZi@h
12.DNA变性是指 vIV|y>;g
A.分子中磷酸二酯键断裂 B.多核苷酸链解裂 C.DNA分子由超螺旋变为双键双螺旋 D.互补碱基之间氢键断裂 0m_yW$w
13.关于关键酶的叙述哪项错误? {7M++J=
A.关键酶常是变构酶 B.关键酶常位于代谢途径的起始或分叉部位 <],{at` v
C.关键酶是共价修饰酶 D.关键酶活性最高 `ASDUgx Mq
14.下列哪个反应是三羧酸循环中的底物水平磷酸化反应:
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A.异柠檬酸—α-酮戊二酸 B.琥珀酰COA—琥珀酸 C.琥珀酸—延胡索酸 D.延胡索酸—苹果酸 Y1PR?c
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15.体内贮存脂肪主要代谢来自 bmG`:_
A.酮体 B.葡萄糖 C.脂肪酸 D.生糖氨基酸 82LE9<4A
16.人体内CO2生成方式是: j`_S%E% X
A.O2与C直接合成 B.O2与CO结合 C.有机酸的脱羧 D.一碳单位与O2结合 o~LJ+m6-)
17.飘零核苷酸从头合成时生成的重要代谢中间物是: NUsxMhP
A.GMP B.AMP C.TMP D.GTP io#}z4"'qY
18.细胞核中分布的酶主要是关于催化代谢的: D$ds[if$U,
A.糖代 B.甘油三酯代 C.蛋白质代 D.核糖代谢 x3O%W?5
19.外显子是: [> HKRVy
A.基因突变的表现 B.DNA被水解断裂片段 C.转录模板链 D.真核生物的编码序列 gVG^R02#<k
20.基因表达调控的基本控制点是: *;A ;)'
A.基因结构活化 B.转录起始 C.转录后加工 D.蛋白质的翻译及译后加工 [:X@|,1V!L
21.从头合成TMP与UMP的共同原料是: Mq>
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A.氨甲酰磷酸 B.磷酸核糖焦磷糖 C.甘氨酰胺核苷酸 D.甲酰甘氨核苷酸 :;%Jm
22.不能氧化酮体的组织是: {hS!IOM
A.心脏 B.肝脏 C.脑 D.肾 k(ouE|B
23.三羧酸循环的限速酶是: (5$Ge$
A.异柠檬酸脱氢酶 B.顺乌头酸酶 C.α-酮戊二酸脱氢酶 D.苹果酸脱氢酶 h#0n2o #
24.脂肪酸合成中的供氧体是: KsULQJ#,
A.FADH2 B.NADH+H+ C.NADPH+H+ D.FMNH2 2!%)_<
25.血浆中胆固醇酯化需要: s<