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主题 : 肿瘤方面考博必读文献
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楼主  发表于: 2023-11-18   
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肿瘤方面考博必读文献

Hallmarks of Cancer: New Dimensions. bX=ht^e [  
      The hallmarks of cancer conceptualization is a heuristic tool for distilling the vast c^Rz?2x  
complexity of cancer phenotypes and genotypes into a provisional set of underly- P/,7CfyPd  
ing principles. As knowledge of cancer mechanisms has progressed, other facets of the disease have ^['%wA%  
emerged as potential refinements. Herein, the prospect is raised that phenotypic plasticity and dis- 2W$c%~j$2  
rupted differentiation is a discrete hallmark capability, and that nonmutational epigenetic reprogram- J0C<Qb[  
ming and polymorphic microbiomes both constitute distinctive enabling characteristics that facilitate \ 02j~r`o  
the acquisition of hallmark capabilities. Additionally, senescent cells, of varying origins, may be added  ORp6   
to the roster of functionally important cell types in the tumor microenvironment.
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